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MARIA PAULA MATOS MARQUES

Foto de Maria Paula Matos Marques   Categoria profissional
Professora Auxiliar da Faculdade de Ciências e Tecnologia da Universidade de Coimbra

Endereço
Departamento de Ciências da Vida
Faculdade de Ciências e Tecnologia
Universidade de Coimbra
Apartado 3046
3001-401 Coimbra

E-mail
pmc@ci.uc.pt

ORCIDiD
ResearcherID
Scopus ID
Research Gate
Curriculum Vitae
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Telefone
+351 239 826 541


Publicações
Increased Breast Cancer Cell Toxicity by Palladination of the Polyamine Analogue N1,N11-bis(ethyl)Norspermine
T.M. Silva, S.M. Fiuza, M.P.M. Marques, L. Persson, S. Oredsson
Amino Acids 46(2), 339-352 (2014)

Carriers for Metal Complexes on Tumour Cells: the Effect of Cyclodextrins vs CNTs on the Model Guest Phenanthroline-5,6-dione Trithiacyclononane Ruthenium Chloride
S.S. Braga, J. Marques, E. Heister, C.V. Diogo, P.J. Oliveira, F.A. Almeida Paz, T.M. Santos, M.P.M. Marques
BioMetals 27(3), 507-525 (2014)

An Inelastic Neutron Scattering Study of Dietary Phenolic Acids
M.P.M. Marques, L.A.E. Batista de Carvalho, R. Valero, N.F.L. Machado, S.F. Parker
Physical Chemistry Chemical Physics 2014(16), 7491-7500 (2014)

Applying Vibrational Spectroscopy to the Study of Nucleobases – Adenine as a Case-Study
R.P. Lopes, R. Valero, J. Tomkinson, M.P.M. Marques, L.A.E. Batista de Carvalho
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 109, 2691-2699 (2013)

Platinum and Palladium-Polyamine Complexes as Anticancer Agents – The Structural Factor
M.P.M. Marques
ISRN Spectroscopy 2013, (2013) 

Norspermidine and Novel Pd(II) and Pt(II) Polynuclear Complexes of Norspermidine as Potential Antineoplastic Agents Against Breast Cancer
T.M. Silva, S. Andersson, S. Kumar, M.P.M. Marques, L. Persson, S. Oredsson
PLoS ONE 8(2), e55651 (2013) 

New Sustained Release Zidovudine Matrix Tablets – Cytotoxicity Towards Caco-2 Cells
J.V. Santos, M.E.T. Pina, M.P.M. Marques, L.A.E. Batista de Carvalho
Drug Development and Industrial Pharmacy 39(8), 1154-1166 (2013) 

A Conformational Study of Hydroxyflavones by Vibrational Spectroscopy Coupled to DFT Calculations
N.F.L. Machado, L.A.E. Batista de Carvalho, J.C. Otero, M.P.M. Marques
The Journal of Physical Chemistry B 117(21), 6421–6429 (2013) 

Polymorphism in Cisplatin Anticancer Drug
M.P.M. Marques, R.Valero, S.F. Parker, J. Tomkinson, L.A.E. Batista de Carvalho
The Journal of Physical Chemistry B 117(21), 6421–6429 (2013)

Antiproliferative Activity of Novel Pd(II) and Pt(II) Polyamine Analogue Complexes in Human Breast Cancer Cell Lines
T. Silva, M.P.M. Marques, P. Woster, L. Persson, S. Oredsson
FEBS Journal 280(S1), 576-577 (2013) 

In silico Methods as a Prominent Tool for Predicting the Potential Biological Activity of Dietary Flavones
N.F.L. Machado, M. Dias, M.P.M. Marques, J.C. Otero
FEBS Journal 280(S1), 539 (2013) 

The Role of Polyamines in the Design of Anticancer Drugs
S.M. Fiuza, A.M. Amado, M.P.M. Marques, L.A.E. Batista de Carvalho
FEBS Journal 280(S1), 312 (2013) 

In Vitro Probing of Human Refractory Prostate Cancer Cells by MicroRaman Spectroscopy
A.L.M. Batista de Carvalho, C.R. Frias, J.C. Otero, M.P.M. Marques
FEBS Journal 280(S1), 311 (2013) 

A Conformational Study of Hydroxylated Isoflavones by Vibrational Spectroscopy Coupled to DFT Calculations
N.F.L. Machado, L.A.E. Batista de Carvalho, J.C. Otero, M.P.M. Marques
Vibrational Spectroscopy 68, 257–265 (2013)

New Strategies Against Prostate Cancer – Pt(II)-Based Chemotherapy
C.S. Matos, A.L.M. Batista de Carvalho, R. Pedro Lopes, M.P.M. Marques
Current Medicinal Chemistry 19(27), 4678-4687 (2012)

Functional and Structural Interactions of Nb, V, Mo and W Oxometalates with the Sarcoplasmic Reticulum Ca2+-ATPase Reveal New Insights Into Inhibition Processes: a Combination of NMR, Raman, AA and EPR Spectroscopies with Kinetic Studies
G. Fraqueza, L. Carvalho, M.P.M. Marques, C.A. Ohlin, W.H. Casey, M. Aureliano
FEBS Journal 279(S1), 439 (2012) 

Novel Pt(II) and Pd(II) Complexes with Polyamine Analogues: Synthesis and Vibrational Analysis
T.M. Silva, S. Oredsson, L. Persson, P. Woster, M.P.M. Marques
Journal of Inorganic Biochemistry 108, 1-7 (2012) 

Isolation, Crystal Structure and Cytotoxicity on Osteosarcoma of a Ruthenium(III) Complex with Coordinated Acetonitrile
J. Marques, J.A. Fernandes, F.A. Almeida Paz, M.P.M. Marques, S.S. Braga
Journal of Coordination Chemistry 65(14), 2489-2499 (2012)

Guanine: A Combined Study Using Vibrational Spectroscopy and Theoretical Methods
R.P. Lopes, M.P.M. Marques, R. Valero, J. Tomkinson, L.A.E. Batista de Carvalho
Spectroscopy: An International Journal 27(5-6),403-413 (2012) 

Conformational Behaviour of Antioxidant Chromones – A Vibrational Spectroscopy Study
N.F.L. Machado, R. Valero, H. Domingos, J. Tomkinson, L.A.E. Batista de Carvalho, J.C. Otero, M.P.M. Marques
Vibrational Spectroscopy 63, 325-337 (2012)

The Autooxidation Process in Linoleic Acid Screened by Raman Spectroscopy
N.F.L. Machado, L.A.E. Batista de Carvalho, J.C. Otero, M.P.M. Marques
Journal of Raman Spectroscopys 43(12), 1991–2000 (2012)

Decavanadate, Decaniobate, Tungstate and Molybdate Interactions with Sarcoplasmic Reticulum Ca2+-ATPase: Quercetin Prevents Cysteine Oxidation by Vanadate but does not Reverse ATPase Inhibition
G. Fraqueza, L.A.E. Batista de Carvalho, M.P.M. Marques, L. Maia, C.A. Ohlin, W.H. Casey, M. Aureliano
Dalton Transactions 41, 12749-12758 (2012)

Pt(II) Complexes with Linear Diamines — Part I: Vibrational Study of Pt-Diaminopropane
A.L.M. Batista de Carvalho, S.M. Fiuza, J. Tomkinson, L.A.E. Batista de Carvalho, M.P.M. Marques
Spectroscopy: An International Journal 27(5-6), 403-413 (2012)

MGBG in Combined Anticancer Chemotherapy
R.F. Goncalves, G. Kriechammer, M.P.M. Marques
Letters in Drug Design & Discovery 8(10), 897-903 (2011)

Characterisation of Antioxidant Olive Oil Biophenols by Vibrational Spectroscopy and Theoretical Calculations
F. Paiva-Martins, V. Rodrigues, R. Calheiros, M.P.M. Marques
Journal of the Science of Food and Agriculture 91(2), 309–314 (2011) 

Chromone-3-Carboxylic Acid as a Potential Electron Scavenger: A Surface-Enhanced Raman Scattering Study
N.F.L. Machado, C. Ruano, J.L. Castro, M.P.M. Marques, J.C. Otero
Physical Chemistry Chemical Physics 13(3), 1012-1018 (2011) 

Arcyriaflavin A Monohydrate
J.A. Fernandes, F.A. Almeida Paz, J. Marques, M.P.M. Marques, S.S. Braga
Acta Crystallographica Section C 67(2), o57–o59 (2011)

DNA Toxicity of Pt(II) and Pd(II) Polyamine Complexes in Human Breast Cancer Cells
T.M. Silva, S. Andersson, M.P.M. Marques, L. Persson and S. Oredsson
European Journal of Cancer 47(Suppl 1), S357 (2011) 

Inelastic Neutron Scattering Study of PtII Complexes Displaying Anticancer Properties
L.A.E. Batista de Carvalho, M.P.M. Marques, C. Martin, S.F. Parker, J. Tomkinson
ChemPhysChem 12(7), 1334–1341 (2011) 

Lipophilic Caffeic and Ferulic Acid Derivatives Presenting Cytotoxicity Against Human Breast Cancer Cells
T.L. Serafim, F.S. Carvalho, M.P.M. Marques, R. Calheiros, T. Silva, J. Garrido, N. Milhazes, F. Borges, F. Roleira, E. Tavares da Silva, J. Holy, P.J. Oliveira
Chemical Research in Toxicology 24(5), 763–774 (2011) 

Biologic Activity of a Dinuclear Pd(II)–Spermine Complex Toward Human Breast Cancer
S.M. Fiuza, J. Holy, L.A.E. Batista de Carvalho, M.P.M. Marques
Chemical Biology & Drug Design 77(6), 477–488 (2011) 

Dietary Chromones as Antioxidant Agents – The Structural Variable
M.M. Dias, N.F.L. Machado, M.P.M. Marques
Food&Function 2(10), 595-602 (2011) 

Structural Studies and Cytotoxicity of Trimethyl(ferrocenylmethyl)ammonium Iodide Encapsulated in β-Cyclodextrin
S.M. Bruno, J.A. Fernandes, J. Marques, S.C. Neto, P.J. Ribeiro-Claro, M. Pillinger, F.A. Almeida Paz, M.P.M. Marques, S.S. Braga, I.S. Gonçalves
European Journal of Inorganic Chemistry 2011(32), 4955–4963 (2011)

Helianthus Tuberosus and Polyamine Research: Past and Recent Applications of a Classical Growth Model
A. Tassoni, N. Bagni, M. Ferri, M. Franceschetti, A. Khomutov, M.P.M. Marques, S.M. Fiuza, A.R. Simonian, D. Serafini-Fracassini
Plant Physiology and Biochemistry 48(7), 496-505 (2010)

Conformational and vibrational study of cis-diamminedichloropalladium(II)
S.M. Fiuza, A.M. Amado, H.F. dos Santos, M.P.M. Marques, L.A.E. Batista de Carvalho
Physical Chemistry Chemical Physics 12, 14309-14321 (2010) 

The Anticancer Properties of Dietary Polyphenols and its Relation with Apoptosis
P. Fresco, F. Borges, M.P.M. Marques, C. Diniz
Current Pharmaceutical Design 16(1), 114-134 (2010) 

Solid State Electrochemical Behaviour of Usnic Acid at a Glassy Carbon Electrode
S.M. Alves Jorge, A.D.R. Pontinha, M.P.M. Marques, A.M. Oliveira-Brett
Analytical Letters 43(10-11), 1713-1722 (2010) 

Polyamines: Fundamental Characters in Chemistry and Biology
E. Agostinelli, M.P.M. Marques, R. Calheiros, F.P.S.C. Gil, G. Tempera, N. Viceconte, V. Battaglia, S. Grancara, A. Toninello
Amino Acids 38(2), 393-403 (2010) 

DNA Interaction with Palladium Chelates of Biogenic Polyamines Using Atomic Force Microscopy and Voltammetric Characterization
O. Corduneanu, A.M. Chiorcea-Paquim, V. Diculescu, S.M. Fiuza, M.P.M. Marques, A.M. Oliveira-Brett
Analytical Chemistry 82(4), 1245–1252 (2010) 

Polynuclear Palladium Complexes with Biogenic Polyamines: AFM and Voltammetric Characterization
O. Corduneanu, A.M. Chiorcea-Paquim, S.M. Fiuza, M.P.M. Marques, A.M. Oliveira-Brett
Bioelectrochemistry 78(2), 97-105 (2010) 

Characterization of Pt-,Pd-Spermine Complexes for their Effect on Polyamine Pathway and Cisplatin Resistance in A2780 Ovarian Carcinoma Cells
R. Tummala, P. Diegelman, S.M. Fiuza, L.A.E. Batista de Carvalho, M.P.M. Marques, D.L. Kramer, K. Clark, S. Vujcic, C.W. Porter, L. Pendyala
Oncology Reports 24(1), 5-24 (2010) 

Lithocholic Acid Derivative as a Model for Artificial Receptors. A Raman Study
F.M.F. Roleira, E.J. Tavares da Silva, R.A. Carvalho, M.P.M. Marques
Letters in Drug Design & Discovery 7(8), 610-617 (2010) 

Nuclear Magnetic Resonance (NMR) Study of the Effect of Cisplatin on the Metabolic Profile of MG-63 Osteosarcoma Cells
I.F. Duarte, I. Lamego, J. Marques, M.P.M. Marques, B.J. Blaise, A.M. Gil
Journal of Proteome Research 9(11), 5877–5886 (2010) 

Analytical Approaches Towards Successful Human Cell Metabolome Studies by NMR Spectroscopy
I.F. Duarte, J. Marques, A.F. Ladeirinha, C. Rocha, I. Lamego, R. Calheiros, T.M. Silva, M.P.M. Marques, J.B. Melo, I.M. Carreira and A.M. Gil
Analytical Chemistry 81(12), 5023–5032 (2009)

A Glycine Ruthenium Trithiacyclononane Complex and its Molecular Encapsulation Using Cyclodextrins
J.T. Marques, A.M. Gil, T.M. Santos, M.P.M. Marques and S.S. Braga
Dalton Transactions 44, 9812-9819 (2009)

Fluoxetine and Norfluoxetine Revisited: New Insights into the Electrochemical and Spectroscopic Properties
E.M. Garrido, J. Garrido, R. Calheiros, M.P.M. Marques and F. Borges
The Journal of Physical Chemistry A 113(36), 9934–9944 (2009) 

Conformational Behaviour of Biologically Active Ferulic Acid Derivatives
R. Calheiros, F. Borges and M.P.M. Marques
Journal of Molecular Structure: THEOCHEM 913(1-3), 146–156 (2009) 

Antioxidant Phenolic Esters with Potential Anticancer Activity: Solution Equilibria Studied by Raman Spectroscopy
N.F.L. Machado, R. Calheiros, A. Gaspar, J. Garrido, F. Borges and M.P.M. Marques
Journal of Raman Spectroscopy 40(1), 80-85 (2009) 

Biogenic Polyamines: The Structural Variable
M.P.M. Marques, A.M.A. Amorim da Costa, J. Tomkinson, R. Calheiros, L.A.E. Batista de Carvalho
Amino Acids 37(Suppl 1), 1956–1965 (2009) 

Biological Activity of Antitumoural MGBG – The Structural Variable
M.P.M. Marques, F.P.S.C. Gil, R. Calheiros, V. Battaglia, A.M. Brunati, A. Toninello
Amino Acids, online first (2008)

Antioxidant Versus Cytotoxic Properties of Hydroxycinnamic Acid Derivatives - A New Paradigm in Phenolic Research
M. Esteves, C. Siquet, A. Gaspar, V. Rio, J.B. Sousa, S. Reis, M.P.M. Marques , F. Borges
Archiv der Pharmazie 341, 164- 173 (2008) 

Antioxidant Phenolic Esters with Potential Anticancer Activity: A Raman Spectroscopy Study
R. Calheiros, N.F.L. Machado, S.M. Fiuza, A. Gaspar, J. Garrido, N. Milhazes, F. Borges, M.P.M. Marques
Journal of Raman Spectroscopy 39, 95-107 (2008)

Complex Formation Between Heptakis(2,6-di-O-methyl)-b-cyclodextrin and Cyclopentadienyl Molybdenum(ii) Dicarbonyl complexes: Structural Studies and Cytotoxicity Evaluations
C.C.L. Pereira, C.V. Diogo, A. Burgeiro, P.J. Oliveira, M.P.M. Marques, S.S. Braga, F.A.A. Paz, M. Pillinger and I.S. Gonçalves
Organometallics 27, 4948-4956 (2008)

Structural studies on supramolecular adducts of cyclodextrins with the complex [Ru([9]aneS3)(bpy)Cl]Cl
J. Marques, L. Anjo, M.P.M. Marques, T.M. Santos, F.A.A. Paz and S.S. Braga
Journal of Organometallic Chemistry 693(18), 3021–3028 (2008)

Voltammetric and DFT Studies on Viloxazine: Analytical Application to Pharmaceuticals and Biological Fluids
E.M.P.J. Garrido, J.M.P.J. Garrido, M. Esteves, A. Santos-Silva, M.P.M. Marques and F. Borges
Electroanalysis 20(13), 1454–1462 (2008)

Use of Effective Core Potential Calculations for the Conformational and Vibrational Study of Platinum(II) Anticancer Drugs. cis-Diamminedichloroplatinum(II) as a Case Study
S. Fiuza, A.M. Amado, M.P.M. Marques and L.A.E. Batista de Carvalho
The Journal of Physical Chemistry A 112(14), 3253–3259 (2008)

Effect of the Metal Center on the Antitumor Activity of the Analogous Dinuclear Spermine Chelates (PdCl2)(2)(Spermine) and (PtCl2)(2)(Spermine)
A.S. Soares, S. Fiuza, M.J. Goncalves,L.A.E. Batista de Carvalho, M.P.M. Marques , A.M. Urbano
Letters in Drug Design & Discovery 4, 460-463 (2007)

Cyclodextrin Encapsulation of Biomimetic Organometallic Cancer Drug Candidates
S.S. Braga, F A.A. Paz, V. Mokal, M. Pillinger, M.P.M. Marques, C.C. Romao, I.S. Goncalves
Drugs of the Future 32, 101 (2007)

Spectroscopic and Electrochemical Studies of Cocaine-Opioid Interactions
J. Garrido, M.P.M. Marques, A.M.S. Silva, T.R.A. Macedo, A.M. Oliveira-Brett, F. Borges
Analytical and Bioanalytical Chemistry 388, 1799-1808 (2007)

Vibrational Spectroscopy Studies on Biologically Relevant Molecules. From Anticancer Agents to Drugs of Abuse
M.P.M. Marques, F. Borges, A.M. Amorim da Costa, L.A.E. Batista de Carvalho
K. Kneip, R. Aroca, H. Kneipp, E. Wentrup-Byrne (Eds.),  In "New Approaches in Biomedical Spectroscopy" , ACS Symposium, série 963, cap.21 (2007)

Electrochemical and Spectroscopic Characterisation of Amphetamine-Like Drugs: Application to the Screening of 3,4-Methylenedioxymethamphetamine (MDMA) and its Synthetic Precursors
N. Milhazes, P. Martins, E. Uriarte, J. Garrido, R. Calheiros, M.P.M. Marques, F. Borges
Analytica Chimica Acta 596, 231-241 (2007)

Phenolic Esters with Potential Anticancer Activity - The Structural Variable
N.F.L. Machado, R. Calheiros, S.M. Fiuza, F. Borges, A. Gaspar, J. Garrido, M.P.M Marques
Journal of Molecular Modeling 13, 865-877 (2007)

Evidence of a Local Order in Concentrated Aqueous Solutions of Salts Constituted by ions of Different Valences. X-ray Diffraction and Raman Spectroscopy Experiments
M.A. Marques, M.I.D. Marques, M.I. Cabaco, A.M. Gaspar, M.P.M. Marques, A.M. Amado, A.M. Amorim da Costa
Journal of Molecular Liquids 134, 142-150 (2007)

Vibrational Spectroscopy Studies on Linear Polyamines
M.P.M. Marques, L.A.E. Batista de Carvalho
Biochemical Society Transactions 35, 374-380 (2007)

Transverse Acoustic Modes of Biogenic and α,ω-polyamines: A Study by Inelastic Neutron Scattering and Raman Spectroscopies Coupled to DFT Calculations
L.A.E. Batista de Carvalho, M.P.M. Marques, J. Tomkinson
Journal of Physical Chemistry A 110, 12947-12954 (2006) 

New Insights on the Anticancer Properties of Dietary Polyphenols
P. Fresco, F. Borges, C. Diniz, M.P.M. Marques
Medicinal Research Reviews 26, 747-766 (2006)

Cytotoxic and COX-2 Inhibition Properties of Hydroxycinnamic Derivatives
M.P.M. Marques, F. Borges, J. Sousa, R. Calheiros, J. Garrido, A. Gaspar, F. Antunes, C. Diniz, P. Fresco
Letters in Drugs Design & Discovery 3, 316-320 (2006)

Drug-Excipient Interactions in Ketoprofen: A Vibrational Spectroscopy Study
L.A.E. Batista de Carvalho, M.P.M. Marques, J. Tomkinson
Biopolymers 82, 420-424 (2006)

Structural Characterization of Agmatine at Physiological Condition
A. Toninello, V. Battaglia, M. Salvi, R. Calheiros, M.P.M. Marques
Structural Chemistry 17, 163-175 (2006)

Pt(II) vs Pd(II) Polyamine Complexes as New Anticancer Drugs: A Structure-Activity Study
S.M. Fiuza, A.M. Amado, L.A.E. Batista de Carvalho, P.J. Oliveira, V.A. Sardão,  M.P.M Marques
Letters in Drug Design & Discovery 3, 149-151 (2006)

Agmatine is Transported in Liver Mitochondria by a Specific Electrophoretic Mechanism
M. Salvi, V. Battaglia, M. Mancon, S. Colombatto, R. Calheiros, M.P.M. Marques, M.A. Grillo, A. Toninello
Biochemical Journal 396, 337-345 (2006)

β-Nitrostyrene Derivatives as Potential Antibacterial Agents: A Structure-Property-Activity Relationship Study
N. Milhazes, R. Calheiros, M.P.M. Marques, J. Garrido, M.N.D.S. Cordeiro, C. Rodrigues, S. Quinteira, C. Novais, L. Peixe, F. Borges
Bioorganic & Medicinal Chemistry 14, 4078-4088 (2006)

Conformational Analysis of the Potential Anticancer Agent Ethyl Trihydroxycinnamate – A Combined Raman Spectroscopy and Ab Initio Study
J.B. Sousa, R. Calheiros, V. Rio, F. Borges, M.P.M. Marques
Journal of Molecular Structure 783, 122-135 (2006)

Structure-Property Studies on the Antioxidant Activity of Flavonoids Present in Diet
S. Teixeira, C. Siquet, C. Alves, I. Boal, M.P.M. Marques, F. Borges, J.L.F.C. Lima, S. Reis
Free Radical Biology Medicine 39, 1099-1108 (2005)

Raman Spectroscopy as a Screening Method for Drugs of Abuse and Their Precursors
M.P.M. Marques, R. Calheiros, N. Milhazes, F. Borges
Clinica Chimica Acta 355, S316-316 (2005)

New Insights on Cocaine-Opiates Interactions
M.P.M. Marques, J.M.P.J. Garrido, A.M.S. Silva, F. Borges, A.M.O. Brett
Clinica Chimica Acta 355, S316-317 (2005)

X-Ray Diffraction Investigations of the Existence of a Local Order in Concentrated Aqueous Solutions of Salts Constituted by Ions of Different Valences
M.I. Cabaço, A.M. Gaspar, M.I. de Barros Marques, M. Alves Marques, M.P.M. Marques, A.M. Amado, A.M. Amorim da Costa
Conference of the European Molecular Liquids Group, Praga, República Checa, (2005)

The Structure of Concentrated Aqueous Solutions of Nitrates of Metallic Cations
M. Alves Marques, M.I. Cabaço, M.I. Barrosa Marques, A.M. Gaspar, M.P.M. Marques, A.M. Amado, A.M. Amorim da Costa
In Proccedings VIth Liquid Matter Conference, Utrech, Holanda, (2005)

Raman Spectroscopy and X-Ray Diffraction Investigations on Concentrated Aqueous Solutions of Metallic Cations
M.I. Cabaço, M. Alves Marques, M.I. Barrosa Marques, A.M. Gaspar, M.P.M. Marques, A.M. Amado, A.M. Amorim da Costa
In Proceedings Thermodynamics 2005 Meeting, Sesimbra, Portugal, (2005)

Local Order in Concentrated Aqueous Solutions of Inorganic Salts Constituted by Ions of Different Valences
M. Alves Marques, M.I. Barrosa Marques, M.I. Cabaço, A.M. Gaspar, M.P.M. Marques, A.M. Amado, A.M. Amorim da Costa
4tyh IUPAC Congress, Beijing, China, 14-19 (2005)

Theoretical Studies on Solid α,ω-Diamine Salts
A.M. Amado, S.M. Fiuza, J.C. Otero, M.P.M. Marques, L.A.E. Batista de Carvalho
Lecture Series on Computer and Computational Sciences 4, 21-24 (2005)

Performance of Different DFT/ECP Combinations in the Study of Platinum Anticancer Drugs
S. Fiúza, A.M. Amado, J.C. Otero, M.P.M. Marques, L.A.E. Batista de Carvalho
Lecture Series on Computer and Computational Sciences 4, 191-194 (2005)

Inclusion of Molybdenocene Dichloride (Cp2MoCl2) in 2-Hydroxypropyl- and Trimethyl-β-cyclodextrin: Structural and Biological Properties
S.S. Braga, J.B. Sousa, M.P.M. Marques, M. Pillinger, J.J. C. Teixeira-Dias, I.S. Gonçalves
Journal of Organometallic Chemistry 690 , 2905-2912 (2005)

Spectroscopic and Theoretical Studies on Solid 1,2-Ethylenediamine Dihydrochloride Salt
A.M. Amado, J.C. Otero, M.P.M. Marques, L.A.E. Batista de Carvalho
ChemPhysChem 5, 1837-1847 (2004)

Identification of Synthetic Precursors of Amphetamine-like Drugs based on Raman Spectroscopy and ab Initio Calculations: β-Methyl-β-nitrostyrene Derivatives
N. Milhazes, F. Borges, R. Calheiros, M.P.M. Marques
The Analyst 129, 1106-1117 (2004)

Phenolic Acid Derivatives with Potential Anticancer Properties – A Structure-Activity Relationship Study. Part 1: Methyl, Propyl and Octyl Esters of Caffeic and Gallic Acids
S.M. Fiuza, C.A. Gomes, L.J. Teixeira, T. Girão da Cruz, M.N. Cordeiro, N. Milhazes, F. Borges, M.P.M. Marques
Bioorganic & Medicinal Chemistry 12, 3581-3589 (2004)

Intra- versus Interchain Interactions in α,ω-Polyamines: A Raman Spectroscopy Study
A.M. Amorim da Costa, M.P.M. Marques, L.A.E. Batista de carvalho
Vibrational Spectroscopy 35, 165-171 (2004)

Cytotoxic Activity of Metal Complexes of Biogenic Polyamines: Polynuclear Platinum(II) Chelates
L.J. Teixeira, M. Seabra, E. Reis, M.T. Girão da Cruz, M.C. Pedroso de Lima, E.
Pereira, M.A. Miranda, M.P.M. Marques
Journal of Medicinal Chemistry 47, 2917-2925 (2004)

Conformational Analysis of a Trihydroxylated Derivative of Cinnamic Acid – A Combined Raman Spectroscopy and Ab Initio Study
S.M. Fiuza, E. Van Besien, N. Milhazes, F. Borges, M.P.M. Marques
Journal of Molecular Structure 693, 103-118 (2004)

β-Nitrostyrene Derivatives - A Conformational Study by Combined Raman Spectroscopy and Ab Initio MO Calculations
R. Calheiros, N. Milhazes, F. Borges, M.P.M. Marques
Journal of Molecular Structure 692, 91-106 (2004)

Conformational Study of Pt(II) Complexes with Polyamines as Possible New Anticancer Agents
M.P.M. Marques, L.A.E. Batista de Carvalho, J. Tomkinson
The Rutherford Appleton Laboratory, ISIS Facility Annual Report (2002-2003)

Anticancer Activity of Phenolic Acids of Natural or Synthetic Origin: A Structure-Activity Study
C.A. Gomes, T. Girão da Cruz, J.L. Andrade, N. Milhazes, F. Borges,  M.P.M.Marques
Journal of Medicinal Chemistry 46,5395-5401 (2003)

Ab Initio Conformational Study of Caffeic Acid
E. Van Besien, M.P.M. Marques
Journal of Molecular Structure (THEOCHEM) 625, 265-275 (2003)

Raman Spectra of Putrescine, Spermidine and Spermine Polyamines and Their N-Deuterated and N-Ionised Derivatives
A.M. Amorim da Costa, M.P.M. Marques, L.A.E. Batista de Carvalho
Journal of Raman Spectroscopy 34, 357-366 (2003)

Conformational Studies on Biogenic Polyamines
M.P.M. Marques, L.A.E. Batista de Carvalho, J. Tomkinson
The Rutherford Appleton Laboratory, ISIS Facility Annual Report (2001-2002)

New Anticancer Agents: Structure-Activity Relationships
M.P.M. Marques, F. Borges, E. Pereira, N. Milhazes, T. Girão, L.J. Teixeira, C. A. Gomes
Drugs of the Future 27 (Suppl. A) 141 (2002)

Study of Carvedilol by Combined Raman Spectroscopy and Ab Initio MO Calculations
M.P.M. Marques, P.J. Oliveira, A.J.M. Moreno, L.A.E. Batista de Carvalho
Journal of Raman Spectroscopy 33 (10), 778-783 (2002)

Experimental and Theoretical Evidence of CH···O Hydrogen Bonding in Liquid 4-Fluorobenzaldehyde
P.J.A. Ribeiro-Claro, M.P.M. Marques, A.M. Amado
ChemPhysChem 3, 599-606 (2002)

The Carbon-Hydrogen Stretching Region of the Raman Spectra of 1,6-Hexane-diamine: N-Deuteration, Ionization and Temperature Effects
A.M. Amorim da Costa, M.P.M. Marques, L.A.E. Batista de Carvalho
Vibrational Spectroscopy 29, 61-67 (2002)

Study of Biogenic and α,ω-Polyamines by Combined Inelastic Neutron Scattering and Raman Spectroscopies, and Ab Initio MO Calculations
M.P.M. Marques, L.A.E. Batista de Carvalho, J. Tomkinson
The Journal of Physical Chemistry A 106, 2473-2482 (2002)

Cytotoxic Effects of Metal Complexes of Biogenic Polyamines. I – Platinum(II) Spermidine Compounds: Prediction of their Antitumour Activity
M.P.M. Marques, T. Girão, M.C. Pedroso de Lima, A. Gameiro, E. Pereira, P. Garcia
Biochimica et Biophysica Acta - Molecular Cell Research 1589 (1), 63-70 (2002)

Evidence of CH···O Hydrogen Bonds in Liquid 4-Ethoxybenzaldehyde by NMR and Vibrational Spectroscopies
M.P.M. Marques, A.M. Amorim da Costa,  P.J.A. Ribeiro-Claro
The Journal of Physical Chemistry A 105, 5292-5297 (2001)

Raman Spectra of Putrescine, Spermidine and Spermine Polyamines and Their N-Deuterated and N-Ionised Derivatives
A.M. Amorim da Costa, M.P.M. Marques, L.A.E. Batista de Carvalho
J. Mink, G. Jalsovszky e G. Keresztury (Eds.). XVIII International Conference on Raman Spectroscopy. John Wiley & Sons Ltd, Chichester, 735 (2002) 

Conformational Analysis of the Protonated Amines [H3N(CH2)nNH3]2+ (n=7 to 10, n=12), Spermidine and Spermine
L.A.E. Batista de Carvalho, M.P.M. Marques, J. Tomkinson
J. Mink, G. Jalsovszky e G. Keresztury (Eds.). XVIII International Conference on Raman Spectroscopy. John Wiley & Sons Ltd, Chichester, 597 (2002) 

Effects of Carvedilol on Isolated Heart Mitochondria: Evidences for a Protonophoretic Mechanism
P.J. Oliveira, M.P.M. Marques, L.A.E. Batista de Carvalho, A.J.M. Moreno
Biochemical and Biophysical Research Communications 276, 82-87 (2000)

Conformational Studies on Biogenic Polyamines
M.P.M. Marques, L.A.E. Batista de Carvalho, J. Tomkinson
The Rutherford Appleton Laboratory, ISIS Facility Annual Report (1999-2000)

Theoretical Approach to the Conformational Preferences of Putrescine
M.P.M. Marques, L.A.E. Batista de Carvalho
D.M.L. Morgan, A. White, F. Sánchez-Jiménez and S. Bardocz (Eds.). COST 917: Biogenically Active Amines in Food. European Commission, Luxembourg, vol. IV, 122-129 (2000)

Study of Copper(II) Polyazamacrocylic Complexes by Electronic Absorption Spectrophotometry and EPR Spectroscopy
C.F.G.C. Geraldes, M.P.M. Marques, Baltazar de Castro, E. Pereira
European Journal of Inorganic Chemistry 2000, 559-565 (2000)

Conformational Analysis of the Protonated Diamines [H3N(CH2)nNH3]2+ (n=2 to 6)
L.A.E. Batista de Carvalho, M.P.M. Marques
S.-L. Zhang e B.-F. Zhu (Eds.). XVII International Conference on Raman Spectroscopy. John Wiley & Sons Ltd, Chichester, 822 (2000)

Structural Studies on Biogenic Polyamines by Combined Raman and INS Spectroscopies and Ab Initio Methods
M.P.M. Marques, L.A.E. Batista de Carvalho, J. Tomkinson
S.-L. Zhang e B.-F. Zhu (Eds.). XVII International Conference on Raman Spectroscopy, John Wiley & Sons Ltd, Chichester, 818 (2000)

Oxygen-by-Sulphur Substitutions in Glycine: Conformational and Vibrational Effects
L.A.E. Batista de Carvalho, M.P.M. Marques, J.J.C. Teixeira-Dias
Journal of the Chemical Society-Perkin Transactions 2, 2507-2514 (1999)

Conformational Study of 1,2-Diaminoethane by Combined Ab Initio MO Calculations and Raman Spectroscopy
L.A.E. Batista de Carvalho, L.E. Lourenço, M.P.M. Marques
Journal of Molecular Structure 482, 639-646 (1999)

Structural Study of Putrescine by Combined Raman Spectroscopy and Ab Initio Methods
M.P.M. Marques, L.A.E. Batista de Carvalho
J. Greve, G.J. Puppels e C. Otto (Eds.), In Spectroscopy of Biological Molecules: New Directions,
Kluwer Academic Publishers, Dordrecht, Holanda, 431 (1999)

Conformational Analysis and Vibrational Frequencies of Alanine and Its Sulphur Tautomers
L.A.E. Batista de Carvalho, M.P.M. Marques, J.J.C. Teixeira-Dias
J. Greve, G.J. Puppels e C. Otto (Eds.), In Spectroscopy of Biological Molecules: New Directions,
Kluwer Academic Publishers, Dordrecht, Holanda, 77 (1999)

Conformational Analysis of Biologically Relevant Diamines by Raman Spectroscopy and Ab Initio MO Calculations
L.A.E. Batista de Carvalho, M.P.M. Marques
A.M. Heyns (Ed.). XVI International Conference on Raman Spectroscopy. John Wiley & Sons Ltd, Chichester, 232 (1998)

NMR Conformational Study of Diamagnetic Complexes of Some Triazatriacetate Macrocycles
Carlos F.G.C. Geraldes, M.P. M. Marques, A.D. Sherry
Inorganica Chimica Acta 273 288-298 (1998)

Conformational and Coordination Equilibria on DOTA Complexes of Lanthanide Metal Ions in Aqueous Solution Studied by 1H-NMR Spectroscopy
S. Aime, M. Botta, M. Fasano, M.P.M. Marques, C.F.G.C. Geraldes, D. Pubanz, A.E. Merbach
Inorganic Chemistry 36, 2059-2068 (1997)

Conformational Analysis of Glycine and its Sulphur Tautomers by Ab Initio MO Methods
L.A.E. Batista de Carvalho, M.P.M. Marques, J.J.C. Teixeira-Dias
P. Carmona, R. Navarro, A. Hernanz (Eds.), Spectroscopy of Biological Molecules: Modern Trends, Kluwer Academic Publishers, Dordrecht, Holanda, 547 (1997)

Conformational Analysis of Piperazine by Vibrational Spectroscopy and Ab Initio Calculations
M.P.M. Marques, L.A.E. Batista de Carvalho
P. Carmona, R. Navarro, A. Hernanz (Eds.), Spectroscopy of Biological Molecules: Modern Trends, Kluwer Academic Publishers, Dordrecht, Holanda, 549 (1997)

Ab initio SCF MO Calculations on Triaza and Tetraaza Cyclic Amines
P.J.A. Ribeiro-Claro, A.M. Amado, M.P.M. Marques, J.J.C. Teixeira-Dias
Journal of the Chemical Society – Perkin Transactions 2, 1161-1167 (1996)

NMR Conformational Study of the Lanthanide(III) Complexes of DOTA in Aqueous Solution
M.P.M Marques, C.F.G.C. Geraldes, A.D. Sherry, A.E. Merbach, H. Powell, D. Pubanz, S. Aime, M. Botta
Journal of Alloys and compounds 225, 303-307 (1995)

Formation and Decomposition Study of Electrochemically generated Ni(III)NOTA Complexes in Aqueous Solution
Baltazar de Castro, J. Gomes, M.P.M Marques, C.F.G.C. Geraldes
Journal of the Chemical Society, Dalton Transactions, 2041-2044 (1995)

Study of the Kinetics of the Formation of the EuDOTA- Complex
M.P.M. Marques, W. D'Olieslager, C.F.G.C. Geraldes
European Journal of Solid State and Inorganic Chemistry 28, 251 (1991)

The Protonation Sequence of Some Triaza Macrocycles Studied by Potentiometry and NMR Spectroscopy
C.F.G.C. Geraldes, A.D. Sherry, M.P.M. Marques, M.C. Alpoim, S. Cortes
Journal of the Chemical Society-Perkin Transactions II, 137-146 (1991)

The Study of Lanthanide-NOTA Chelates as Aqueous Paramagnetic Probes in Structural Nuclear Magnetic Resonance Spectroscopy
C.F.G.C. Geraldes, M.P.M. Marques, A.D. Sherry
Ciência Biológica 12, 82 (1987)

A NMR Study of Lanthanide-NOTA Chelates as Aqueous Paramagnetic Shift and Relaxation Probes
C.F.G.C. Geraldes, M.P.M. Marques, A.D. Sherry
Inorganica Chimica Acta 139, 311-313 (1987)

A NMR Study of Ln(NOTA) Chelates as Axially Symmetric Aqueous Shift Reagents
C.F.G.C. Geraldes, M.C. Alpoim, M.P.M. Marques, A.D. Sherry,  M. Singh
Revista Portuguesa de Química 27, 346 (1985)

Nuclear Magnetic Resonance and Potentiometric Studies of the Protonation Scheme of a Triaza Triacetic Macrocycle and its Complexes with Lanthanum and Lutetium
C.F.G.C. Geraldes, M.C. Alpoim, M.P.M. Marques, A.D. Sherry, M. Singh
Inorganic Chemistry 24, 3876-3881 (1985)


Projectos
Novas Abordagens Terapêuticas no Cancro: Desenho Racional e Síntese de Novos Ligandos dos Receptores A3 da Adenosina (PTDC/QUI/70359/2006)

Hibridização Molecular no Desenvolvimento de Novas Drogas Anticancerígenas (CAPES/CPLP-4.1.3.)

Síntese de Metabolitos de Drogas de Abuso (Opiáceos). Avaliação das Interacções entre os Metabolitos dos Opiáceos e a Cocaína” (Fundação Ilídio Pinho, Portugal, 2006)


Health Implications of Dietary Amines (Acção COST 922 - WG 2)

Aplicação de um Novo Método Natural na Prevenção do Abrolhamento e Monitorização em Tempo Real da Maturação de Alimentos de Origem Vegetal” (AGRO 8.1/691)

Desenvolvimento de Novos Agentes Anticancerígenos: Derivados Fenólicos de Origem Natural ou Sintética – Relações Estrutura-Actividade (POCI/QUI/55631/2004)

Estudo Bioquímico e Comportamental das Interacções Opiácios – Cocaína (POCI/SAU-FCF/58330/2004)

Complexos de Pt(II) com Poliaminas Biogénicas como Novos Agentes Anticancerígenos: Relações Estrutura-Actividade (POCTI/QUI/47256/2002)

Estudo de Poliaminas Biogénicas e de seus Complexos Metálicos (POCTI/QUI/33199/2000)


Ligações de Hidrogénio C-H...O em Líquidos (POCTI/35408/QUI/00)

Análise Conformacional de Poliaminas: Estudo por Espectroscopia Vibracional e Cálculos Ab Initio (PBIC/C/QUI/2219/95)

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